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MyBiosource Biotechnology normal human and diabetic pancreatic tissues
Anatomy of lymphatics in normal and diseased human <t>pancreatic</t> islets. (A) No LYVE-1 islet-associated staining was detected in tissue from normal donors. (B and C) Lymphatics were present in islets from type 1 diabetes donors. (D) Similar to the NOD mouse lesion, CD4 T cells accumulated on the outside of the islet and were associated to lymphatic vessels. (E) Based on the intensity of the insulin stain, the successive steps of the human lesion are shown in a single specimen in which, from left to right, normal islets, lymphatic-associated islets, and nearly and fully destroyed islets were found. Zoomed-in regions where LYVE-1 staining was present showed the intimate relationship between lymphatics and the outside of the islet. Scale bars, 50 µm.
Normal Human And Diabetic Pancreatic Tissues, supplied by MyBiosource Biotechnology, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/normal human and diabetic pancreatic tissues/product/MyBiosource Biotechnology
Average 90 stars, based on 1 article reviews
normal human and diabetic pancreatic tissues - by Bioz Stars, 2026-05
90/100 stars

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1) Product Images from "Repositioning the Early Pathology of Type 1 Diabetes to the Extraislet Vasculature"

Article Title: Repositioning the Early Pathology of Type 1 Diabetes to the Extraislet Vasculature

Journal: The Journal of Immunology Author Choice

doi: 10.4049/jimmunol.2300769

Anatomy of lymphatics in normal and diseased human pancreatic islets. (A) No LYVE-1 islet-associated staining was detected in tissue from normal donors. (B and C) Lymphatics were present in islets from type 1 diabetes donors. (D) Similar to the NOD mouse lesion, CD4 T cells accumulated on the outside of the islet and were associated to lymphatic vessels. (E) Based on the intensity of the insulin stain, the successive steps of the human lesion are shown in a single specimen in which, from left to right, normal islets, lymphatic-associated islets, and nearly and fully destroyed islets were found. Zoomed-in regions where LYVE-1 staining was present showed the intimate relationship between lymphatics and the outside of the islet. Scale bars, 50 µm.
Figure Legend Snippet: Anatomy of lymphatics in normal and diseased human pancreatic islets. (A) No LYVE-1 islet-associated staining was detected in tissue from normal donors. (B and C) Lymphatics were present in islets from type 1 diabetes donors. (D) Similar to the NOD mouse lesion, CD4 T cells accumulated on the outside of the islet and were associated to lymphatic vessels. (E) Based on the intensity of the insulin stain, the successive steps of the human lesion are shown in a single specimen in which, from left to right, normal islets, lymphatic-associated islets, and nearly and fully destroyed islets were found. Zoomed-in regions where LYVE-1 staining was present showed the intimate relationship between lymphatics and the outside of the islet. Scale bars, 50 µm.

Techniques Used: Staining



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MyBiosource Biotechnology normal human and diabetic pancreatic tissues
Anatomy of lymphatics in normal and diseased human <t>pancreatic</t> islets. (A) No LYVE-1 islet-associated staining was detected in tissue from normal donors. (B and C) Lymphatics were present in islets from type 1 diabetes donors. (D) Similar to the NOD mouse lesion, CD4 T cells accumulated on the outside of the islet and were associated to lymphatic vessels. (E) Based on the intensity of the insulin stain, the successive steps of the human lesion are shown in a single specimen in which, from left to right, normal islets, lymphatic-associated islets, and nearly and fully destroyed islets were found. Zoomed-in regions where LYVE-1 staining was present showed the intimate relationship between lymphatics and the outside of the islet. Scale bars, 50 µm.
Normal Human And Diabetic Pancreatic Tissues, supplied by MyBiosource Biotechnology, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/normal human and diabetic pancreatic tissues/product/MyBiosource Biotechnology
Average 90 stars, based on 1 article reviews
normal human and diabetic pancreatic tissues - by Bioz Stars, 2026-05
90/100 stars
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Anatomy of lymphatics in normal and diseased human pancreatic islets. (A) No LYVE-1 islet-associated staining was detected in tissue from normal donors. (B and C) Lymphatics were present in islets from type 1 diabetes donors. (D) Similar to the NOD mouse lesion, CD4 T cells accumulated on the outside of the islet and were associated to lymphatic vessels. (E) Based on the intensity of the insulin stain, the successive steps of the human lesion are shown in a single specimen in which, from left to right, normal islets, lymphatic-associated islets, and nearly and fully destroyed islets were found. Zoomed-in regions where LYVE-1 staining was present showed the intimate relationship between lymphatics and the outside of the islet. Scale bars, 50 µm.

Journal: The Journal of Immunology Author Choice

Article Title: Repositioning the Early Pathology of Type 1 Diabetes to the Extraislet Vasculature

doi: 10.4049/jimmunol.2300769

Figure Lengend Snippet: Anatomy of lymphatics in normal and diseased human pancreatic islets. (A) No LYVE-1 islet-associated staining was detected in tissue from normal donors. (B and C) Lymphatics were present in islets from type 1 diabetes donors. (D) Similar to the NOD mouse lesion, CD4 T cells accumulated on the outside of the islet and were associated to lymphatic vessels. (E) Based on the intensity of the insulin stain, the successive steps of the human lesion are shown in a single specimen in which, from left to right, normal islets, lymphatic-associated islets, and nearly and fully destroyed islets were found. Zoomed-in regions where LYVE-1 staining was present showed the intimate relationship between lymphatics and the outside of the islet. Scale bars, 50 µm.

Article Snippet: Normal human and diabetic pancreatic tissues were obtained from the Network for Pancreatic Organ Donors with Diabetes (nPOD) program and MyBiosource.

Techniques: Staining